Hello fellow hemp lovers! Today, we’re shining a spotlight on CBDa (cannabidiolic acid)—the little-known, raw, pure precursor to CBD. At Hemp Kissed, our infusions are proudly CBDa-based, meaning you’re getting the full, live-from-the-plant goodness, without heating, chemical extraction, or altering those delicate compounds.
Let’s get into why that matters to us—and what research says.
What Is CBDa?
CBDa is the acidic precursor to CBD. It is produced naturally in fresh hemp. Unlike CBD, it hasn’t been decarboxylated (i.e., heated), so it retains a different molecular structure—and therefore different benefits. Think of it as CBD in its purest, most organic form.
Why CBDa Deserves Your Attention
Thanks to early research, we’re learning that CBDa isn’t just a “pre-CBD.” It may have unique benefits of its own:
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Anti-inflammatory power — via the same pathway as NSAIDs
CBDa appears to work on the COX-2 enzyme pathway—the same one targeted by common over-the-counter anti-inflammatory drugs like ibuprofen and aspirin. By influencing this pathway, CBDa may reduce inflammation at the source, offering a natural alternative that taps into the body’s own systems.
📖 Study on CBDa as a selective COX-2 inhibitor - Breast Cancer Findings
CBDa shows the ability to inhibit the migration of highly invasive forms of breast cancer cells
📖 Study on CBDa as an inhibitor of breast cancer cell migration -
Nausea and digestive support
CBDa has shown promise in reducing nausea—especially anticipatory nausea (like what chemotherapy patients may experience)—thanks to its strong action on serotonin (5-HT1A) receptors.
📖 Project CBD overview, Study on CBDa's effect of nausea and vomiting -
Mood balance
That same serotonin receptor activity is linked to mood, which may explain why some people report uplift and calm when using CBDa.
📖 Study on CBDa's effect of depression-like behavior -
Neuroprotective promise
In preclinical models, CBDa has shown potential in protecting neurons and supporting healthy brain function.
📖 CBDa in Alzheimer’s models
Why Our Infusions Embrace CBDa
At Hemp Kissed, we infuse raw hemp to preserve CBDa’s integrity. That means no heating, no chemicals, no degradation—just pure, plant-forward potency. Our CBDa-based infusions bring you:
- Maximum preservation of delicate cannabinoids in their pure form
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A product free of solvents and chemicals
- The entourage effect as provided directly from the hemp plant
The Hemp Kissed Promise
We love hemp in all its forms, but we're purists so CBDa holds a special place in our hearts. It’s natural, unprocessed, and packed with plant-based superpowers—just how nature intended. As proponents of purity, we also value transparency. In our blog, we want to share the information we have learned, where it came from, and how it influences our products.
We'll keep the information coming -- until next time fellow hemp lovers!